Crestor and Acute Kidney Damage Side Effects

Recent studies have raised concerns about the safety of the cholesterol drug Crestor, due to data suggesting the medications may be linked to life-threatening side effects, including acute kidney damage. Crestor (rosuvastatin) has been on the market since 2003 and is currently manufactured by drug maker AstraZeneca Pharmaceuticals. Crestor belongs to a class of drugs called HMG CoA reductase inhibitors, or statins, which function by reducing cholesterol and triglycerides, a type of fat in the blood. Crestor is also commonly used to reduce the risk of stroke, heart attack and other heart problems in patients with diabetes and coronary heart disease. Unfortunately, researchers have indicated that even the standard starting dosage of the potent statin, Crestor, may expose patients to an unnecessarily high dose of the drug, potentially leading to serious side effects. If you took Crestor and have since suffered from a major side effect, like acute kidney damage, contact a Crestor attorney to discuss your legal options.

Acute Kidney Damage Symptoms

The kidneys are critical to the proper functioning of the body, and are responsible for ridding the body of waste products. Acute kidney damage or failure is characterized by a sudden, rapid loss of kidney function, sometimes occurring as a side effect of some pharmaceutical medications. Common symptoms of acute kidney damage include:

  • Fatigue
  • Fluid retention
  • Chest pain
  • Shortness of breath
  • Diarrhea

Acute kidney damage is typically diagnosed by the following criteria: occurring in a short period of time (typically within 48 hours) and a reduction in kidney function, which is characterized by a decrease in urine output.

Acute Kidney Damage Treatment and Prognosis

The proper treatment for acute kidney damage includes determining and treating the underlying cause of the condition. The proper treatment depends on the severity of the damage sustained by the kidneys. Common goals of acute kidney damage treatment include:

  • Correcting dehydration by administering intravenous fluids
  • Increasing blood flow to kidneys
  • Correcting chemical (electrolyte) abnormalities

Most causes of acute kidney damage can be treated successfully, and kidney function can return to normal with time. In some cases, replacement of kidney function by dialysis may be necessary until proper kidney function has returned.

FDA Warnings and Crestor Side Effect Studies

In 2005, the FDA issued a public health advisory warning patients and healthcare professionals about the risk of kidney failure and rhabdomyolysis, or serious muscle damage, in patients taking statins like Crestor. In response to Crestor side effect information, the FDA required AstraZeneca to update the Crestor label to include the risk of possible increased muscle toxicity associated with Crestor, and the possible adverse effects on the kidneys. Researchers at the Tufts-New England Medical Center compared the safety profiles of the three most commonly prescribed statins, and determined that Crestor had the poorest safety profile. The most serious side effects potentially linked to Crestor use were muscle damage (rhabdomyolysis) and kidney damage, which frequently required hospitalization. Due to the potential for Crestor to cause serious side effects in patients, researchers involved in this study, which was published in the Journal of the American Heart Association, urged healthcare professionals to consider other statins besides Crestor as first-line therapy for high cholesterol.

Crestor Attorneys for Kidney Damage Side Effects

Acute kidney damage can be extremely dangerous, potentially leading to chronic kidney failure, end-stage kidney disease and other life-threatening side effects. If you or a loved one has suffered from a side effect which you believe to be linked to Crestor, contact an experienced Crestor attorney to discuss your legal options. You may be entitled to financial compensation for your injuries, medical expenses, and pain and suffering, which you can collect by filing a Crestor lawsuit against AstraZeneca. The main goal of Crestor attorneys is to help victims of alleged Crestor side effects protect their rights and hold the allegedly negligent drug company liable for their injuries. Pharmaceutical companies like AstraZeneca are expected to produce and distribute safe medications, and should be held accountable for any adverse side effects sustained by consumers of their products. Unfortunately, this isn't always the case. By hiring a qualified Crestor lawyer to represent your case, you can collect the compensation you deserve and protect yourself and your family from further harm.

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