Actos Side Effects

Actos side effects may be linked to bladder cancer and heart disease that could lead to heart failure.  Actos attorneys are filing lawsuits nationwide on behalf of Actos side effects victims.  Talk to an Actos lawyer today if you have been affected by these harmful side effects.

According to recent studies, the popular diabetes drug Actos may be linked to an increased risk of severe side effects like bladder cancer, heart failure, heart disease and cardiovascular risk among patients. In fact, new Actos side effect information indicates that, compared to never being exposed to Actos, a duration of Actos therapy longer than 12 months has been associated with a 40% increased risk of bladder cancer. Actos is commonly used in the treatment of type 2 diabetes in adults, in combination with diet and exercise, and has been on the U.S. market since it was FDA-approved for that use in 1999. Actos (pioglitazone) belongs to a class of drugs called thiazolidinediones, and helps lower blood glucose levels by increasing the sensitivity of muscle, fat and liver cells to insulin. Actos is currently manufactured by drug company Takeda Pharmaceuticals North America Inc. Unfortunately, with the release of new information about the increased risk of bladder cancer side effects, Actos may no longer be considered a safe treatment for some patients. If you took Actos to treat your type 2 diabetes and have since suffered from one or more severe side effects, contact an Actos attorney to discuss your legal options.

Bladder Cancer Side Effects

The most prevalent side effect potentially associated with Actos use is bladder cancer, which is caused by a cancerous tumor located in the bladder. Common symptoms of bladder cancer include painful urination, abdominal pain, and blood in the urine, as well as fatigue, bone pain or tenderness, and weight loss. It is estimated that twenty out of 100,000 Americans suffer from bladder cancer each year, and the risk is believed to be higher in patients with diabetes. The prognosis for bladder cancer victims depends largely on the initial stage of the cancer and the patient's response to treatment. Patients with stage 0 or stage I have a fairly good chance of making a recovery, although the risk of the cancer returning is high. The cure rate for patients with stage III tumors is less than 50%, and patients with stage IV bladder cancer are rarely cured. Bladder cancer can spread into nearby organs, and can also travel through the pelvic lymph nodes and spread to the bones, liver and lungs. Other side effects potentially linked to Actos use in patients include cardiovascular risks of heart disease possibly leading to heart failure or heart attack.

Actos FDA Warnings

After reviewing a five-year interim analysis of an ongoing ten-year epidemiological study regarding the connection between Actos and bladder cancer, the FDA issued a safety announcement regarding the increased risk of bladder cancer side effects in patients who use the diabetes medication Actos for more than one year. According to the results of this analysis, an increased risk of bladder cancer was noted among patients with the longest exposure to Actos, and in those exposed to the highest cumulative dose of Actos. Another epidemiological study was conducted in France with similar results, which led to the removal of Actos from the market in France and the recommendation against starting Actos in new patients in Germany.

The only other thiazolidinedione, called Avandia, was removed from the U.S. market earlier this year in response to studies linking the drug to an increased risk of cardiovascular side effects, including heart attacks. In light of new Actos side effect information, the FDA has advised healthcare professionals to avoid prescribing Actos to patients with active bladder cancer, and to use Actos with caution in patients with a prior history of bladder cancer. The FDA urges patients and physicians to weigh the benefits of blood sugar control against the unknown risks for cancer recurrence when considering the use of Actos.

Actos Attorneys for Side Effect Help

If you or a loved one has suffered from a severe side effect like bladder cancer and you believe Actos to be the cause, contact an Actos attorney to discuss your legal options. You may be entitled to financial compensation for your injuries, medical expenses, and pain and suffering, which you can collect by filing an Actos lawsuit against Takeda Pharmaceuticals. The main goal of Actos attorneys is to help injured victims protect their rights and prevent further harm at the hands of big drug companies. Too often, victims of pharmaceutical drug injuries are taken advantage of during their time of need. By hiring an experienced Actos lawyer to represent your case, you can bring public attention to the potentially harmful nature of Actos, and collect the financial compensation you deserve.

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